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24.4) clapping the chest wall overlying thearea of pathology (Stiller 2000). For this reason,endocrine glands are well vascularized and surrounded byrich vascular networks
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These publishedmodels should be consulted for further detail on the approachfor applying the PBPK methodology in specific cases. Investiga-tions should include brain imaging without and withcontrast to rule out structural lesions.