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Thelatter raises issues of re-administration of the same or an alternative/different vectorto resurrect lost transgene expression and address the cause of the disease. The rapid shallow mode of breath-ing, therefore, appears to be economical in termsof work expenditure when compliance is low(Otis et al
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2004) and used a “collaps-ibility” index to help guide ?uid administration inventilated patients with sepsis (Vieillard-Baronet al.
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